Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8787565 | 0.85 | — | — | |
| SCHEMBL7551488 | 0.82 | CYP2C19 (0.38) | — | |
| SCHEMBL3654075 | 0.81 | ALDH1A1 (0.35) | PKM | |
| SCHEMBL7002732 | 0.80 | — | — | |
| SCHEMBL7548873 | 0.80 | — | — | |
| SCHEMBL5474500 | 0.79 | ALDH1A1 (0.39) | PKM | |
| SCHEMBL7620230 | 0.78 | TDP1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL20502496 | 0.77 | ALDH1A1 (0.38) | — | |
| SCHEMBL10054542 | 0.76 | TSHR (0.38) | — | |
| SCHEMBL29703000 | 0.73 | PKM (0.31) | PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1158982-A4 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2002-06-12 | — | — | EP | disclosed |
| US-6376496-B1 | TREATMENT OF CANCER | MERCK & CO., INC. | 2002-04-23 | — | — | US | disclosed |
| EP-1158982-A2 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000052134-A2 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2000-09-08 | — | — | WO | disclosed |