SCHEMBL754576

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL752207	0.85	EDNRA (0.52)	KDM4EALDH1A1LMNAMAPTNPSR1
	SCHEMBL16925412	0.84	KDM4E (0.57)	KDM4EAHRPLK1ALDH1A1LMNA
	Hydrochloric Acid SCHEMBL754760	0.84	EDNRA (0.51)	KDM4EALDH1A1LMNAMAPTNPSR1
	SCHEMBL754304	0.84	KDM4E (0.63)	KDM4EAHRPLK1ALDH1A1LMNA
	SCHEMBL9223032	0.83	GLO1 (0.57)	KDM4EALDH1A1LMNAMAPTNPSR1
	SCHEMBL754759	0.83	KDM4E (0.49)	KDM4EALDH1A1LMNAMAPTNPSR1
	SCHEMBL27744144	0.83	KDM4E (0.49)	KDM4EALDH1A1LMNAMAPTNPSR1
	SCHEMBL4169298	0.81	KDM4E (0.47)	KDM4EAHRPLK1LMNAMAPT
	SCHEMBL19744020	0.79	KDM4E (0.68)	KDM4EAHRPLK1ALDH1A1LMNA
	SCHEMBL29502927	0.79	KDM4E (0.56)	KDM4EALDH1A1LMNAMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.