Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 5/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 3/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 5/20 | 0.37 |
| ▸ | CTSL | P07711 | 4/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545843 | 1.00 | ANPEP (0.43) | ANPEPMMP1HDAC3HDAC4HDAC1 | |
| SCHEMBL7543392 | 0.93 | MMP2 (0.40) | MMP1LMNAMMP3CTSLMMP2 | |
| SCHEMBL7543387 | 0.93 | MMP2 (0.40) | MMP1LMNAMMP3CTSLMMP2 | |
| SCHEMBL7541536 | 0.92 | ANPEP (0.43) | ANPEPMMP1HDAC3HDAC4HDAC1 | |
| SCHEMBL7541538 | 0.92 | ANPEP (0.43) | ANPEPMMP1HDAC3HDAC4HDAC1 | |
| SCHEMBL7539469 | 0.92 | MMP2 (0.38) | ANPEPMMP1LMNAMMP3CTSL | |
| SCHEMBL7539472 | 0.92 | MMP2 (0.38) | ANPEPMMP1LMNAMMP3CTSL | |
| SCHEMBL7540417 | 0.92 | CTSL (0.37) | MMP1MMP3CTSLMMP2MAPT | |
| SCHEMBL7540421 | 0.92 | CTSL (0.37) | MMP1MMP3CTSLMMP2MAPT | |
| SCHEMBL7542130 | 0.92 | ANPEP (0.42) | ANPEPMMP1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |