Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4525774 | 0.83 | CYP2B6 (0.47) | CHRM3CHRM2CHRM1CYP2B6MAPT | |
| Cadaverine Tartrate SCHEMBL4521162 | 0.75 | CYP2B6 (0.40) | KIF11CHRM3GAACYP2B6MAPT | |
| SCHEMBL9273398 | 0.73 | KMT2A (0.46) | CHRM3CHRM2CHRM1MAPTKMT2A | |
| SCHEMBL10360491 | 0.71 | MAPT (0.43) | CHRM3CHRM2MAPTKMT2ALMNA | |
| SCHEMBL4276964 | 0.70 | CHRM3 (0.58) | CHRM3GAACYP2B6KMT2AMEN1 | |
| SCHEMBL10360494 | 0.69 | MAPT (0.38) | CHRM3CHRM2CHRM1CYP2B6MAPT | |
| SCHEMBL10360472 | 0.67 | MAPT (0.46) | KIF11CHRM3CHRM2CHRM1MAPT | |
| SCHEMBL11019030 | 0.67 | CHRM3 (0.43) | CHRM3CHRM2CHRM1GAACYP2B6 | |
| SCHEMBL6266546 | 0.67 | CYP2B6 (0.56) | CHRM3CYP2B6MAPTKMT2ANPSR1 | |
| SCHEMBL11903252 | 0.67 | CYP2D6 (0.46) | KIF11CHRM3CHRM2CHRM1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |