Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548682 | 0.91 | RAB9A (0.52) | AGPAT2TP53PDE10AALOX5APALOX5 | |
| SCHEMBL7541413 | 0.88 | LMNA (0.47) | AGPAT2TP53PDE10AALOX5APALOX5 | |
| SCHEMBL7542484 | 0.88 | MAPT (0.52) | TP53PDE10ARAB9AALDH1A1TSHR | |
| SCHEMBL7541142 | 0.88 | PDE10A (0.45) | AGPAT2TP53PDE10AALOX5APALOX5 | |
| SCHEMBL27486934 | 0.86 | PDE10A (0.44) | AGPAT2TP53PDE10AALOX5APALOX5 | |
| SCHEMBL7541593 | 0.85 | PDE10A (0.43) | AGPAT2TP53PDE10AALOX5APALOX5 | |
| SCHEMBL7544331 | 0.84 | RAB9A (0.46) | PDE10ARAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7542952 | 0.82 | SMN1; SMN2 (0.57) | AGPAT2TP53PDE10AALOX5RAB9A | |
| SCHEMBL7544792 | 0.80 | AGPAT2 (0.51) | AGPAT2TP53ALOX5EPHX2ALDH1A1 | |
| SCHEMBL7544713 | 0.79 | AGPAT2 (0.60) | AGPAT2TP53EGFRPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795550-B1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0795550-A1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |