Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 6/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7553596 | 0.92 | HPSE (0.48) | CYP3A4CYP2D6ACHEDPP7CHEK1 | |
| SCHEMBL7554505 | 0.88 | MAP4K4 (0.48) | CYP3A4CYP2D6ACHEDPP7HDAC6 | |
| SCHEMBL7554506 | 0.86 | ACHE (0.62) | CYP2D6ACHEDPP7HPSEKDM4E | |
| SCHEMBL7546717 | 0.82 | ACHE (0.54) | ACHEDPP7CCR2HDAC6PARP1 | |
| SCHEMBL7549557 | 0.82 | DPP7 (0.49) | CYP3A4CYP2D6ACHEDPP7PARP1 | |
| SCHEMBL7552057 | 0.81 | DPP7 (0.41) | CYP3A4CYP2D6ACHEDPP7MAP3K8 | |
| SCHEMBL7549395 | 0.81 | ACHE (0.50) | ACHEDPP7CCR2HDAC6MAP3K8 | |
| SCHEMBL7553785 | 0.81 | CCR2 (0.62) | ACHEDPP7CCR2HDAC6PARP1 | |
| SCHEMBL7550044 | 0.80 | ACHE (0.65) | CYP3A4ACHEDPP7CCR2HDAC6 | |
| SCHEMBL7548588 | 0.80 | ACHE (0.49) | ACHEDPP7CCR2HDAC6CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020099054-A1 | 2-phenyl benzimidazole derivatives as MCP-1 antagonists | WARNER-LAMBERT COMPANY (US) | 2002-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099054-A1 | 2-phenyl benzimidazole derivatives as MCP-1 antagonists | CCR1, CCR2, CCR8 | CYP3A4 1292/4885CYP2D6 2355/4885ACHE 4652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.