Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ESRRB | O95718 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539409 | 0.98 | AAK1 (0.56) | AAK1KMT2ATSHRGAAMIF | |
| SCHEMBL8136302 | 0.89 | AAK1 (0.48) | AAK1KMT2ATSHRGAAMIF | |
| SCHEMBL8125424 | 0.89 | AAK1 (0.48) | AAK1KMT2ATSHRGAAMIF | |
| SCHEMBL12091642 | 0.84 | AAK1 (0.50) | AAK1KMT2ATSHRGAAMIF | |
| SCHEMBL12087979 | 0.84 | AAK1 (0.50) | AAK1KMT2ATSHRGAAMIF | |
| SCHEMBL25166096 | 0.83 | AAK1 (0.50) | AAK1KMT2ATSHRGAAMIF | |
| SCHEMBL11114111 | 0.83 | AAK1 (0.50) | AAK1KMT2ATSHRGAAMIF | |
| SCHEMBL7401142 | 0.83 | AAK1 (0.50) | AAK1KMT2ATSHRGAAMIF | |
| SCHEMBL8199100 | 0.83 | AAK1 (0.50) | AAK1KMT2ATSHRALDH1A1PRSS1 | |
| SCHEMBL2210789 | 0.82 | MIF (0.54) | AAK1KMT2ATSHRGAAMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |