Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 4/20 | 0.34 |
| ▸ | FAP | Q12884 | 4/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546114 | 1.00 | HRH3 (0.41) | HRH3POLBL3MBTL1EPHX1HPGD | |
| SCHEMBL7542036 | 0.85 | POLB (0.59) | HRH3POLBL3MBTL1EPHX1HPGD | |
| SCHEMBL7542043 | 0.85 | POLB (0.59) | HRH3POLBL3MBTL1EPHX1HPGD | |
| SCHEMBL24067460 | 0.83 | ALDH1A1 (0.48) | HRH3POLBL3MBTL1HPGDKMT2A | |
| SCHEMBL7545915 | 0.81 | POLB (0.55) | HRH3POLBL3MBTL1EPHX1HPGD | |
| SCHEMBL7545912 | 0.81 | POLB (0.55) | HRH3POLBL3MBTL1EPHX1HPGD | |
| SCHEMBL7546055 | 0.81 | POLB (0.55) | HRH3POLBL3MBTL1EPHX1HPGD | |
| SCHEMBL7545768 | 0.76 | HCRTR2 (0.39) | HRH3POLBL3MBTL1PREPALDH1A1 | |
| SCHEMBL7541055 | 0.76 | HCRTR2 (0.39) | HRH3POLBL3MBTL1PREPALDH1A1 | |
| SCHEMBL20038765 | 0.76 | EPHX1 (0.38) | HRH3EPHX1HPGDKMT2APREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |