Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 9/20 | 0.35 |
| ▸ | FAP | Q12884 | 5/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541055 | 1.00 | HCRTR2 (0.39) | HCRTR2HRH3ALDH1A1ATMDPP4 | |
| SCHEMBL2546757 | 0.79 | POLB (0.41) | HCRTR2DPP4FAPNPC1RAB9A | |
| SCHEMBL2788731 | 0.79 | POLB (0.41) | HCRTR2DPP4FAPNPC1RAB9A | |
| SCHEMBL24067460 | 0.79 | ALDH1A1 (0.48) | HRH3ALDH1A1NPC1RAB9APOLB | |
| SCHEMBL793131 | 0.79 | POLB (0.41) | HCRTR2DPP4FAPNPC1RAB9A | |
| SCHEMBL7542669 | 0.79 | SMN1; SMN2 (0.45) | HCRTR2DPP4DPP7RAB9APOLB | |
| SCHEMBL15653975 | 0.78 | DAGLB (0.40) | HCRTR2NPC1RAB9APOLBL3MBTL1 | |
| SCHEMBL3699146 | 0.78 | DAGLB (0.40) | HCRTR2NPC1RAB9APOLBL3MBTL1 | |
| SCHEMBL7542043 | 0.77 | POLB (0.59) | HRH3ALDH1A1DPP4POLBL3MBTL1 | |
| SCHEMBL7542036 | 0.77 | POLB (0.59) | HRH3ALDH1A1DPP4POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |