Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22926184 | 0.88 | MC4R (0.51) | MC4RPOLBGAAMEN1KMT2A | |
| SCHEMBL20805978 | 0.88 | MC4R (0.51) | MC4RPOLBGAAMEN1KMT2A | |
| SCHEMBL5657812 | 0.83 | ITGA4 (0.44) | MC4RLMNAPOLBTACR1 | |
| SCHEMBL5657809 | 0.83 | ITGA4 (0.44) | MC4RLMNAPOLBTACR1 | |
| SCHEMBL5972730 | 0.83 | ITGA4 (0.44) | MC4RLMNAPOLBTACR1 | |
| SCHEMBL2297284 | 0.83 | POLB (0.56) | MC4RLMNAPOLBNPSR1TACR1 | |
| SCHEMBL830669 | 0.83 | POLB (0.56) | MC4RLMNAPOLBNPSR1TACR1 | |
| SCHEMBL830668 | 0.83 | POLB (0.56) | MC4RLMNAPOLBNPSR1TACR1 | |
| SCHEMBL13093279 | 0.76 | SLC6A4 (0.48) | MC4RTACR1 | |
| SCHEMBL16350188 | 0.74 | POLB (0.56) | MC4RPOLBNPSR1TACR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |