Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 7/20 | 0.63 |
| ▸ | MPL | P40238 | 3/20 | 0.51 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.42 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21508484 | 0.84 | KMO (0.50) | KMOAAK1CYP11B1CYP11B2CTSS | |
| SCHEMBL447519 | 0.81 | KMO (0.64) | KMOTRPV3MAPTL3MBTL1 | |
| SCHEMBL24761199 | 0.80 | MPL (0.59) | KMOMPLF2RL3 | |
| SCHEMBL19072716 | 0.80 | KMO (0.56) | KMOMPLCYP11B1CYP11B2CTSS | |
| SCHEMBL29751892 | 0.76 | KMO (0.45) | KMOMPLAAK1CTSSCTSK | |
| SCHEMBL443863 | 0.76 | KIF11 (0.47) | KMOTRPV3MAPTL3MBTL1GABRA1 | |
| SCHEMBL7626033 | 0.75 | KMO (0.55) | KMOMPLCTSSCTSKTRPV3 | |
| SCHEMBL31375122 | 0.75 | KMO (0.61) | KMOAAK1MAPTL3MBTL1 | |
| SCHEMBL19072718 | 0.75 | KMO (0.55) | KMOMPLCTSSCTSKTRPV3 | |
| SCHEMBL3756448 | 0.75 | KMO (0.48) | KMOAAK1CYP11B1CYP11B2TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6440984-B1 | PROTECTION FOR GROWING AND HARVESTED CROPS; CONTROLLING TOBACCO BUDWORMS AND SOUTHERN ARMYWORMS; PESTICIDES; INSECTICIDES; MITICIDES; ANTHELMINTICS | BASF AKTIENGESELLSCHAFT (DE) | 2002-08-27 | — | — | US | disclosed |
| US-20020045634-A1 | Use of aryl-substituted pyrimidines as insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY | 2002-04-18 | — | — | US | disclosed |
| US-6306866-B1 | 2-ALKOXY SUBSTITUTED PYRIMIDINE DERIVATIVES | AMERICAN CYANAMID COMPANY | 2001-10-23 | — | — | US | disclosed |
| US-6153619-A | Aryl-substituted pyrimidines as insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 2000-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045634-A1 | Use of aryl-substituted pyrimidines as insecticidal and acaricidal agents | YBX1, YBX3, CYP1B1 | KMO 1317/4885MPL 1811/4885AAK1 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.