Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 3/20 | 0.39 |
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546505 | 1.00 | ALDH1A1 (0.41) | ALDH1A1ACEMMECPA1ACE2 | |
| SCHEMBL28090209 | 0.87 | ALDH1A1 (0.45) | ALDH1A1ACEMMECPA1ACE2 | |
| SCHEMBL6231002 | 0.87 | ALDH1A1 (0.36) | ALDH1A1ACEMMECPA1ACE2 | |
| SCHEMBL3499612 | 0.82 | ALDH1A1 (0.42) | ALDH1A1ACEMMECPA1ACE2 | |
| SCHEMBL13311446 | 0.82 | ALDH1A1 (0.42) | ALDH1A1ACEMMECPA1ACE2 | |
| SCHEMBL2625119 | 0.80 | ALDH1A1 (0.41) | ALDH1A1ACEMMECPA1ACE2 | |
| SCHEMBL8569856 | 0.80 | TP53 (0.41) | ALDH1A1ACEMMECPA1ACE2 | |
| SCHEMBL20753231 | 0.80 | ALDH1A1 (0.41) | ALDH1A1ACEMMECPA1ACE2 | |
| SCHEMBL30751935 | 0.80 | ALDH1A1 (0.41) | ALDH1A1ACEMMECPA1ACE2 | |
| SCHEMBL13145129 | 0.78 | TSHR (0.41) | ALDH1A1ACEMMECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020156320-A1 | Enantioselective synthesis of valproic acid analogues | NAU HEINZ (DE) | 2002-10-24 | — | — | US | claimed |
| US-20020156320-A1 | Enantioselective synthesis of valproic acid analogues | NAU HEINZ (DE) | 2002-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156320-A1 | Enantioselective synthesis of valproic acid analogues | COASY, ACADM, CYP2A6 | ALDH1A1 422/4885ACE 155/4885MME 3372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.