Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 3/20 | 0.39 |
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28090209 | 0.87 | ALDH1A1 (0.45) | TP53ALDH1A1ACEMMECPA1 | |
| SCHEMBL13145129 | 0.83 | TSHR (0.41) | TP53ALDH1A1ACEMMECPA1 | |
| SCHEMBL14748307 | 0.83 | TSHR (0.41) | TP53ALDH1A1ACEMMECPA1 | |
| SCHEMBL3499612 | 0.82 | ALDH1A1 (0.42) | TP53ALDH1A1ACEMMECPA1 | |
| SCHEMBL13311446 | 0.82 | ALDH1A1 (0.42) | TP53ALDH1A1ACEMMECPA1 | |
| SCHEMBL7546505 | 0.80 | ALDH1A1 (0.41) | TP53ALDH1A1ACEMMECPA1 | |
| SCHEMBL2625119 | 0.80 | ALDH1A1 (0.41) | TP53ALDH1A1ACEMMECPA1 | |
| SCHEMBL20753231 | 0.80 | ALDH1A1 (0.41) | TP53ALDH1A1ACEMMECPA1 | |
| SCHEMBL7546501 | 0.80 | ALDH1A1 (0.41) | TP53ALDH1A1ACEMMECPA1 | |
| SCHEMBL48925 | 0.78 | TP53 (0.39) | TP53ALDH1A1ACETSHRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830936-A | THERMAL STABILIZERS FOR POLYOLEFINS AND ENGINEERING PLASTICS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-11-03 | — | — | US | disclosed |