Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | CPA1 | P15085 | 2/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449920 | 0.86 | EPHX2 (0.45) | EPHX2TDP1SMN1; SMN2EPHX1HPGD | |
| SCHEMBL7449915 | 0.86 | EPHX2 (0.45) | EPHX2TDP1SMN1; SMN2EPHX1HPGD | |
| SCHEMBL839468 | 0.83 | ALPI (0.53) | TDP1KDM4EHPGDCPA1NPC1 | |
| SCHEMBL839467 | 0.83 | ALPI (0.53) | TDP1KDM4EHPGDCPA1NPC1 | |
| SCHEMBL4842827 | 0.83 | ALPI (0.53) | TDP1KDM4EHPGDCPA1NPC1 | |
| SCHEMBL27523629 | 0.81 | THRB (0.42) | EPHX2SMN1; SMN2KDM4EEPHX1ALDH1A1 | |
| Dl-Phenylalanine SCHEMBL9318540 | 0.80 | SLC7A5 (0.65) | EPHX2TDP1SMN1; SMN2EPHX1HPGD | |
| Phenylalanine SCHEMBL9318542 | 0.80 | SLC7A5 (0.65) | EPHX2TDP1SMN1; SMN2EPHX1HPGD | |
| SCHEMBL9395382 | 0.79 | ALPI (0.49) | TDP1KDM4EHPGDMMECPA1 | |
| SCHEMBL9395387 | 0.79 | PKM (0.49) | TDP1KDM4EHPGDCPA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056715-B1 | PROCESS FOR PREPARING 2-ACETYLTHIO-3-PHENYL-PROPIONIC ACID AND THE SALTS THEREOF | ZAMBON SPA (IT) | 2002-06-12 | — | — | EP | disclosed |
| EP-1056715-A1 | PROCESS FOR PREPARING 2-ACETYLTHIO-3-PHENYL-PROPIONIC ACID AND THE SALTS THEREOF | ZAMBON GROUP S.p.A. (IT) | 2000-12-06 | — | — | EP | disclosed |
| US-6080881-A | Process for preparing 2-acetythio-3-phenyl-propionic acid and the salts thereof | ZAMBON GROUP S.P.A. (IT) | 2000-06-27 | — | — | US | disclosed |
| WO-1999042438-A1 | PROCESS FOR PREPARING 2-ACETYLTHIO-3-PHENYL-PROPIONIC ACID AND THE SALTS THEREOF | ZAMBON GROUP S.P.A. (IT) | 1999-08-26 | — | — | WO | disclosed |