SCHEMBL7546526

SCHEMBL7546526

CCCCCC1NC(=O)C(=O)N1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.38
ABL1 P00519 2/20 0.38
RIN1 Q13671 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
TP53 P04637 1/20 0.36
ALDH1A1 P00352 4/20 0.35
HLCS P50747 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
MAPT P10636 2/20 0.34
KDM4E B2RXH2 1/20 0.34
PKM P14618 1/20 0.34
HPGD P15428 1/20 0.34
PRKCD Q05655 4/20 0.33
PTGS1 P23219 3/20 0.32
PTGS2 P35354 3/20 0.32
MGLL Q99685 2/20 0.32
FAAH O00519 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19683169 0.69 ALDH1A1 (0.37) GAAABL1RIN1TDP1TP53
SCHEMBL2426639 0.68 ALDH1A1 (0.47) GAATP53ALDH1A1HLCSL3MBTL1
SCHEMBL169504 0.67 ABL1 (0.41) GAAABL1RIN1TDP1TP53
SCHEMBL4785937 0.67 PRKCD (0.39) GAAABL1RIN1TDP1ALDH1A1
SCHEMBL7887401 0.66 PTGS1 (0.42) GAATP53ALDH1A1PRKCDPTGS1
SCHEMBL15141796 0.65 TSHR (0.40) GAAALDH1A1THRB
SCHEMBL15141713 0.65 TSHR (0.40) GAAALDH1A1THRB
SCHEMBL5452034 0.65
SCHEMBL15142530 0.65 TSHR (0.40) GAAALDH1A1THRB
SCHEMBL15141860 0.65 TSHR (0.40) GAAALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1209525-A1 CHEMICAL AMPLIFICATION RESIST COMPOSITION Mitsubishi Rayon Co., Ltd. (JP) 2002-05-29 EP disclosed