Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCD | Q05655 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | HLCS | P50747 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20429180 | 0.77 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1ALOX5HLCSABL1 | |
| SCHEMBL8998171 | 0.71 | GBA1 (0.40) | PRKCDALDH1A1L3MBTL1ALOX5HLCS | |
| SCHEMBL19751784 | 0.68 | PRKCD (0.41) | PRKCDALDH1A1L3MBTL1ALOX5MGLL | |
| SCHEMBL7546526 | 0.67 | GAA (0.38) | PRKCDALDH1A1L3MBTL1HLCSABL1 | |
| SCHEMBL1140659 | 0.67 | GNAO1 (0.38) | GAA | |
| SCHEMBL169504 | 0.67 | ABL1 (0.41) | ALDH1A1L3MBTL1HLCSABL1GAA | |
| SCHEMBL20954139 | 0.66 | GNAO1 (0.41) | GAA | |
| SCHEMBL19683169 | 0.66 | ALDH1A1 (0.37) | PRKCDALDH1A1L3MBTL1HLCSABL1 | |
| SCHEMBL20954130 | 0.66 | GNAO1 (0.41) | GAA | |
| SCHEMBL4461377 | 0.65 | ALDH1A1 (0.69) | PRKCDALDH1A1L3MBTL1HLCSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |