Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6487506 | 0.85 | PTGS2 (0.57) | PTGS2ALOX5PTGS1WDR5MAPT | |
| SCHEMBL6477173 | 0.74 | PTGS2 (0.59) | PTGS2ALOX5PTGS1 | |
| SCHEMBL697719 | 0.67 | TAAR1 (0.44) | MAPT | |
| SCHEMBL7493792 | 0.64 | PTGS2 (0.33) | PTGS2ALOX5PTGS1 | |
| SCHEMBL6477263 | 0.62 | PTGS2 (0.71) | PTGS2ALOX5PTGS1WDR5 | |
| SCHEMBL6476564 | 0.62 | PTGS2 (0.68) | PTGS2ALOX5PTGS1 | |
| SCHEMBL6291354 | 0.62 | PTGS2 (0.68) | PTGS2ALOX5PTGS1 | |
| SCHEMBL6484222 | 0.60 | PTGS2 (1.00) | PTGS2ALOX5PTGS1 | |
| SCHEMBL10629178 | 0.60 | ESR2 (0.48) | ALOX5MAPT | |
| SCHEMBL9458601 | 0.59 | PTGS2 (0.57) | PTGS2ALOX5PTGS1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246825-A1 | FUSED PYRROLE COMPOUNDS, PHARMACEUTICAL AGENTS CONTAINING THE SAME, AND THE USE THEREOF | MERCKLE GMBH (DE) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001051491-A1 | FUSED PYRROLE COMPOUNDS, PHARMACEUTICAL AGENTS CONTAINING THE SAME, AND THE USE THEREOF | MERCKLE GMBH (DE) | 2001-07-19 | — | — | WO | disclosed |