SCHEMBL7546607

SCHEMBL7546607

N=C(CO)Cc1ccc(O)c(O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.53
MAPT P10636 6/20 0.53
HIF1A Q16665 4/20 0.53
HSD17B10 Q99714 4/20 0.53
TDP1 Q9NUW8 4/20 0.53
GAA P10253 3/20 0.53
THPO P40225 3/20 0.53
LMNA P02545 3/20 0.53
HPGD P15428 3/20 0.53
BLM P54132 3/20 0.53
PMP22 Q01453 3/20 0.53
APEX1 P27695 2/20 0.53
POLB P06746 2/20 0.53
NFKB1 P19838 2/20 0.53
RGS12 O14924 1/20 0.53
TSHR P16473 1/20 0.53
GNAI1 P63096 1/20 0.53
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA4 P22748 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18250216 0.78 CNR2 (0.44) KDM4EMAPTHIF1AHSD17B10TDP1
SCHEMBL29501893 0.77 KDM4E (0.55) KDM4EMAPTHIF1AHSD17B10TDP1
SCHEMBL9313056 0.77 KDM4E (0.55) KDM4EMAPTHIF1AHSD17B10TDP1
SCHEMBL29262781 0.75 KDM4E (0.64) KDM4EMAPTHIF1AHSD17B10TDP1
SCHEMBL30575218 0.75 KDM4E (0.64) KDM4EMAPTHIF1AHSD17B10TDP1
SCHEMBL17124775 0.75 GABRA1 (0.41) KDM4EMAPTTDP1GAAHPGD
SCHEMBL10595930 0.72 KDM4E (0.67) KDM4EMAPTHIF1AHSD17B10TDP1
SCHEMBL29404315 0.72 CA1 (0.67) KDM4EMAPTHIF1AHSD17B10TDP1
SCHEMBL68232 0.72 CA1 (0.67) KDM4EMAPTHIF1AHSD17B10TDP1
SCHEMBL23752251 0.72 KDM4E (0.66) KDM4EMAPTHIF1AHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0752117-B1 RETROREFLECTIVE ARTICLE AND METHOD OF MAKING THE SAME MINNESOTA MINING & MFG (US) 2002-06-12 EP disclosed
US-5474827-A Wash and wear fabric comprising an aromatic bidentate compound being chemical bonding to reflective metal and binder MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-12-12 US disclosed