Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | THPO | P40225 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | BLM | P54132 | 3/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | APEX1 | P27695 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | RGS12 | O14924 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313056 | 1.00 | KDM4E (0.55) | KDM4EMAPTTDP1HIF1AHSD17B10 | |
| SCHEMBL2734611 | 0.78 | KDM4E (0.67) | KDM4EMAPTTDP1HIF1AHSD17B10 | |
| SCHEMBL1520671 | 0.77 | TSHR (0.63) | TDP1GAALMNANFKB1TSHR | |
| SCHEMBL9312616 | 0.77 | HTR3E (0.44) | KDM4EMAPTTDP1HIF1AHSD17B10 | |
| SCHEMBL7546607 | 0.77 | KDM4E (0.53) | KDM4EMAPTTDP1HIF1AHSD17B10 | |
| Dopamine SCHEMBL4826995 | 0.75 | KDM4E (0.84) | KDM4EMAPTTDP1HIF1AHSD17B10 | |
| SCHEMBL9313028 | 0.75 | KDM4E (0.52) | KDM4EMAPTTDP1HIF1AHSD17B10 | |
| SCHEMBL1520205 | 0.75 | CA2 (0.60) | KDM4ETDP1LMNABLMCA2 | |
| SCHEMBL2810781 | 0.75 | HTR3E (0.73) | LMNACYP2D6HTR3EHTR3BHTR3A | |
| SCHEMBL10595930 | 0.74 | KDM4E (0.67) | KDM4EMAPTTDP1HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615963-A1 | GENETICALLY MODIFIED BENZYLISOQUINOLINE ALKALOID-PRODUCING HOST CELLS WITH MODIFIED EFFLUX TRANSPORTER GENE EXPRESSION | River Stone Biotech ApS (DK) | 2025-09-17 | — | — | EP | claimed |
| US-20250179543-A1 | NORCOCLAURINE SYNTHASES WITH INCREASED ACITVITY | RIVER STONE BIOTECH INC (US) | 2025-06-05 | — | — | US | claimed |
| US-12203118-B2 | Norcoclaurine synthases with increased activity | RIVER STONE BIOTECH, INC. (US) | 2025-01-21 | — | — | US | claimed |
| US-12030043-B2 | Photoactive product comprising a catechol-containing compound and a photoelectrode comprising same | MCMASTER UNIVERSITY (CA) | 2024-07-09 | — | — | US | claimed |
| WO-2024100063-A1 | GENETICALLY MODIFIED BENZYLISOQUINOLINE ALKALOID-PRODUCING HOST CELLS WITH MODIFIED EFFLUX TRANSPORTER GENE EXPRESSION | RIVER STONE BIOTECH APS (DK) | 2024-05-16 | — | — | WO | claimed |
| US-20240150805-A1 | Glycosylated Opioids | RIVER STONE BIOTECH APS (DK) | 2024-05-09 | — | — | US | claimed |
| EP-4334441-A1 | GLYCOSYLATED OPIOIDS | River Stone Biotech ApS (DK) | 2024-03-13 | — | — | EP | claimed |
| EP-4076733-B1 | PEROVSKITE SOLAR CELL PROVIDED WITH AN ADSORBENT MATERIAL FOR ADSORBING TOXIC MATERIALS | ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) | 2024-02-07 | — | — | EP | claimed |
| US-20230332195-A1 | GENETICALLY MODIFIED HOST CELLS PRODUCING BENZYLISOQUINOLINE ALKALOIDS | RIVER STONE BIOTECH APS (DK) | 2023-10-19 | — | — | US | claimed |
| US-20230193333-A1 | Norcoclaurine Synthases With Increased Activity | RIVER STONE BIOTECH, INC. | 2023-06-22 | — | — | US | claimed |
| CN-115427142-A | Perovskite solar cell provided with adsorbing material for adsorbing toxic substances | 洛桑联邦理工学院(EPFL) | 2022-12-02 | — | — | CN | claimed |
| WO-2022234005-A1 | GLYCOSYLATED OPIOIDS | RIVER STONE BIOTECH APS (DK) | 2022-11-10 | — | — | WO | claimed |
| US-20220347665-A1 | PHOTOACTIVE PRODUCT COMPRISING A CATECHOL-CONTAINING COMPOUND AND A PHOTOELECTRODE COMPRISING SAME | MCMASTER UNIVERSITY (CA) | 2022-11-03 | — | — | US | claimed |
| EP-4041891-A1 | GENETICALLY MODIFIED HOST CELLS PRODUCING BENZYLISOQUINOLINE ALKALOIDS | River Stone Biotech ApS (DK) | 2022-08-17 | — | — | EP | claimed |
| WO-2022150380-A1 | ALKALOID PRODUCING OXIDASES AND CARBOXY-LYASES AND METHODS OF USE | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2022-07-14 | — | — | WO | claimed |
| EP-4727572-A1 | COMPOSITIONS COMPRISING COLLAGENASE AND USES THEREOF IN ORTHODONTIC PROCEDURES | Ramot at Tel-Aviv University Ltd. (IL) | 2026-04-22 | — | — | EP | disclosed |
| US-20260083641-A1 | COMPOSITIONS COMPRISING COLLAGENASE AND USES THEREOF IN ORTHODONTIC PROCEDURES | UNIV RAMOT (IL) | 2026-03-26 | — | — | US | disclosed |
| WO-2022109194-A1 | METHODS OF IMPROVING PRODUCTION OF MORPHINAN ALKALOIDS AND DERIVATIVES | ANTHEIA, INC. (US) | 2022-05-27 | — | — | WO | disclosed |
| US-20220112528-A1 | RECOMBINANT HOST CELLS WITH IMPROVED PRODUCTION OF L-DOPA, DOPAMINE, S-NOROCLAURINE OR DERIVATIVES THEREOF | RIVER STONE BIOTECH APS (DK) | 2022-04-14 | — | — | US | disclosed |
| CN-114262681-A | Berberine producing strain, and establishing method and application thereof | 中国科学院分子植物科学卓越创新中心 | 2022-04-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260083641-A1 | COMPOSITIONS COMPRISING COLLAGENASE AND USES THEREOF IN ORTHODONTIC PROCEDURES | MMP13, MMP2, MMP24 | KDM4E 460/4885MAPT 827/4885TDP1 1055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.