Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.45 |
| ▸ | PPARG | P37231 | 10/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540604 | 0.88 | ALDH1A1 (0.42) | PPARAPPARGFFAR1ALDH1A1KDM4E | |
| SCHEMBL7547501 | 0.87 | PPARA (0.49) | PPARAPPARGFFAR1PPARD | |
| SCHEMBL5385326 | 0.84 | FFAR1 (0.49) | PPARAPPARGFFAR1ALDH1A1KDM4E | |
| SCHEMBL7546654 | 0.84 | PPARA (0.47) | PPARAPPARGFFAR1ALDH1A1KDM4E | |
| SCHEMBL5397484 | 0.82 | FFAR1 (0.48) | PPARAPPARGFFAR1ALDH1A1KDM4E | |
| SCHEMBL5385319 | 0.82 | PPARA (0.49) | PPARAPPARGFFAR1ALDH1A1KDM4E | |
| SCHEMBL7546657 | 0.81 | PPARA (0.46) | PPARAPPARGFFAR1ALDH1A1KDM4E | |
| SCHEMBL5379026 | 0.80 | FFAR1 (0.48) | PPARAPPARGFFAR1ALDH1A1KDM4E | |
| SCHEMBL5377697 | 0.80 | FFAR1 (0.61) | PPARAPPARGFFAR1ALDH1A1KDM4E | |
| SCHEMBL5376806 | 0.80 | FFAR1 (0.48) | PPARAPPARGFFAR1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228067-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGYLCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001038325-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-31 | — | — | WO | disclosed |