Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546686 | 1.00 | SLC7A5 (0.33) | SLC7A5TP53ADAMTS4CA2GABRR1 | |
| SCHEMBL19520956 | 0.76 | ADAMTS4 (0.36) | SLC7A5TP53ADAMTS4CA2CA1 | |
| SCHEMBL825142 | 0.73 | — | — | |
| SCHEMBL7478210 | 0.71 | SLC1A3 (0.42) | SLC7A5GABRR1 | |
| Hydrochloric Acid SCHEMBL31663435 | 0.71 | CA1 (0.35) | CA2CA1 | |
| Sulfuric Acid SCHEMBL15799557 | 0.70 | TP53 (0.36) | SLC7A5TP53ADAMTS4 | |
| SCHEMBL2553365 | 0.69 | — | — | |
| Hydrazine SCHEMBL2231845 | 0.69 | TP53 (0.40) | SLC7A5TP53GABRR1 | |
| SCHEMBL11996286 | 0.69 | TP53 (0.40) | SLC7A5TP53 | |
| SCHEMBL1548945 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214301-A1 | HYPOGLYCEMIC N,N-ARYLSULFONYLGLYCINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001016119-A1 | HYPOGLYCEMIC N,N-ARYLSULFONYLGLYCINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-03-08 | — | — | WO | disclosed |