Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329195 | 0.81 | CA12 (0.37) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28305733 | 0.76 | SLC1A3 (0.45) | SLC1A3SLC1A2SLC1A1GABRR1BLM | |
| SCHEMBL7546686 | 0.71 | SLC7A5 (0.33) | GABRR1SLC7A5 | |
| SCHEMBL7546694 | 0.71 | SLC7A5 (0.33) | GABRR1SLC7A5 | |
| SCHEMBL19520956 | 0.67 | ADAMTS4 (0.36) | SLC7A5 | |
| SCHEMBL825142 | 0.65 | — | — | |
| SCHEMBL8653443 | 0.64 | ALDH1A1 (0.32) | — | |
| SCHEMBL21447936 | 0.63 | AAK1 (0.39) | SLC1A3SLC1A2SLC1A1BLM | |
| SCHEMBL26212136 | 0.63 | CA1 (0.36) | — | |
| SCHEMBL27872491 | 0.63 | SLC7A5 (0.45) | SLC1A3SLC1A2SLC1A1SLC7A5PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801648-A4 | SUBSTITUTED 2-ARYLCARBONYLOXYMETHYL-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE DERIVATIVES AND COMPOSITIONS AND METHOD OF USE THEREOF | SANOFI WINTHROP INC (US) | 1998-01-28 | — | — | EP | disclosed |
| EP-0801648-A1 | SUBSTITUTED 2-ARYLCARBONYLOXYMETHYL-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE DERIVATIVES AND COMPOSITIONS AND METHOD OF USE THEREOF | SANOFI WINTHROP, INC. (US) | 1997-10-22 | — | — | EP | disclosed |
| WO-1996016951-A1 | SUBSTITUTED 2-ARYLCARBONYLOXYMETHYL-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE DERIVATIVES AND COMPOSITIONS AND METHOD OF USE THEREOF | SANOFI WINTHROP, INC. (US) | 1996-06-06 | — | — | WO | disclosed |