Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546837 | 1.00 | CHRNB4 (0.32) | CHRNB4CHRNA3ELANEHDAC3HDAC4 | |
| SCHEMBL7546849 | 1.00 | CHRNB4 (0.32) | CHRNB4CHRNA3ELANEHDAC3HDAC4 | |
| SCHEMBL9717611 | 0.98 | CHRNB4 (0.33) | CHRNB4CHRNA3 | |
| SCHEMBL1006893 | 0.90 | CHRNB4 (0.35) | CHRNB4CHRNA3ELANE | |
| SCHEMBL1006892 | 0.90 | CHRNB4 (0.35) | CHRNB4CHRNA3ELANE | |
| SCHEMBL30315864 | 0.85 | CHRNB4 (0.32) | CHRNB4CHRNA3 | |
| SCHEMBL11594509 | 0.84 | — | — | |
| SCHEMBL11594512 | 0.84 | — | — | |
| Biphenyl SCHEMBL6138056 | 0.77 | ALDH1A1 (0.50) | — | |
| Biphenyl SCHEMBL27668291 | 0.77 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210349-A | Catalytic hydrogenation using ruthenium catalyst | PHILLIPS PETROLEUM COMPANY (US) | 1993-05-11 | — | — | US | claimed |
| US-5171907-A | Preparation of hydrogenation catalyst and hydrogenation process therewith | PHILLIPS PETROLEUM COMPANY (US) | 1992-12-15 | — | — | US | claimed |
| US-5128296-A | Using activated ruthenium catalyst complexes | PHILLIPS PETROLEUM COMPANY (US) | 1992-07-07 | — | — | US | claimed |
| EP-1008573-B1 | Process for the hydrogenation of polyenes to monoenes | BASF AG (DE) | 2002-06-12 | — | — | EP | disclosed |
| US-6194624-B1 | HYDROGENATING POLYENES TO CORRESPONDING MONOENES USING HOMOGENEOUS RUTHENIUM CATALYSTS IN PRESENCE OF CARBOXYLIC ACID | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-27 | — | — | US | disclosed |
| EP-1008573-A1 | Process for the hydrogenation of polyenes to monoenes | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-14 | — | — | EP | disclosed |
| US-5210349-A | Catalytic hydrogenation using ruthenium catalyst | PHILLIPS PETROLEUM COMPANY (US) | 1993-05-11 | — | — | US | disclosed |
| US-5171907-A | Preparation of hydrogenation catalyst and hydrogenation process therewith | PHILLIPS PETROLEUM COMPANY (US) | 1992-12-15 | — | — | US | disclosed |