SCHEMBL9717611

SCHEMBL9717611

C1=CC=CCCCCC(c2ccccc2)=CC=C1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
PTGS2 P35354 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7546837 0.98 CHRNB4 (0.32) CHRNB4CHRNA3
SCHEMBL7546849 0.98 CHRNB4 (0.32) CHRNB4CHRNA3
SCHEMBL7546844 0.98 CHRNB4 (0.32) CHRNB4CHRNA3
SCHEMBL1006893 0.92 CHRNB4 (0.35) CHRNB4CHRNA3PTGS2TDP1TSHR
SCHEMBL1006892 0.92 CHRNB4 (0.35) CHRNB4CHRNA3PTGS2TDP1TSHR
SCHEMBL30315864 0.87 CHRNB4 (0.32) CHRNB4CHRNA3
SCHEMBL11594509 0.81
SCHEMBL11594512 0.81
Biphenyl SCHEMBL6138056 0.79 ALDH1A1 (0.50) TDP1
Biphenyl SCHEMBL27668291 0.79 ALDH1A1 (0.50) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5128296-A Using activated ruthenium catalyst complexes PHILLIPS PETROLEUM COMPANY (US) 1992-07-07 US disclosed