Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.51 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13534290 | 0.84 | MAPT (0.55) | MAPTALDH1A1L3MBTL1LMNABAZ2B | |
| SCHEMBL15798471 | 0.83 | KDM4E (0.51) | MAPTALDH1A1LMNAGAAKMT2A | |
| SCHEMBL7545848 | 0.77 | KDM3B (0.46) | MAPTALDH1A1GAAPOLBKMT2A | |
| SCHEMBL18640322 | 0.76 | KDM4E (0.37) | MAPTGAAKMT2AMEN1KDM4E | |
| SCHEMBL20653919 | 0.74 | KMT2A (0.51) | MAPTALDH1A1L3MBTL1LMNABAZ2B | |
| SCHEMBL8121938 | 0.72 | ALDH1A1 (0.60) | MAPTALDH1A1L3MBTL1LMNAGAA | |
| SCHEMBL1810204 | 0.72 | KMT2A (0.61) | MAPTALDH1A1L3MBTL1LMNAGAA | |
| SCHEMBL388418 | 0.72 | BAZ2B (0.61) | MAPTALDH1A1L3MBTL1LMNABAZ2B | |
| SCHEMBL26608016 | 0.72 | ALDH1A1 (0.51) | MAPTALDH1A1L3MBTL1LMNAGAA | |
| SCHEMBL31091468 | 0.71 | KMT2A (0.58) | MAPTALDH1A1L3MBTL1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802194-B1 | Novel thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORP (JP) | 2002-06-19 | — | — | EP | disclosed |
| US-5795497-A | Thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORPORATION (JP) | 1998-08-18 | — | — | US | disclosed |
| EP-0802194-A2 | Novel thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORPORATION (JP) | 1997-10-22 | — | — | EP | disclosed |