Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.46 |
| ▸ | DDO | Q99489 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.38 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18640322 | 0.84 | KDM4E (0.37) | KDM3BKDM4EGAAMAPTCYP2C9 | |
| SCHEMBL8672229 | 0.81 | KMT2A (0.45) | KDM3BDDOKDM4EGAAHSD17B10 | |
| SCHEMBL15798471 | 0.81 | KDM4E (0.51) | KDM4EGAAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL815121 | 0.77 | KDM3B (0.42) | KDM3BDDOKDM4EGAAHSD17B10 | |
| SCHEMBL7547086 | 0.77 | MAPT (0.53) | KDM4EGAAHSD17B10ALDH1A1RXFP1 | |
| SCHEMBL9054601 | 0.74 | KDM3B (0.39) | KDM3BDDOKDM4EGAAHSD17B10 | |
| SCHEMBL4761435 | 0.68 | IKBKB (0.46) | KDM3BDDOKDM4EGAAHSD17B10 | |
| SCHEMBL14438658 | 0.67 | ALDH1A1 (0.44) | KDM4EGAAHSD17B10ALDH1A1MAPT | |
| SCHEMBL25424962 | 0.67 | KMT2A (0.42) | DDOKDM4EGAAHSD17B10HPGD | |
| SCHEMBL10823650 | 0.66 | KMT2A (0.53) | DDOKDM4EGAAHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295454-A | Targeting chromosomal instability and downstream cytoplasmic DNA signaling to treat cancer | 康奈尔大学 | 2020-06-16 | — | — | CN | disclosed |
| EP-0802194-B1 | Novel thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORP (JP) | 2002-06-19 | — | — | EP | disclosed |
| US-5795497-A | Thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORPORATION (JP) | 1998-08-18 | — | — | US | disclosed |
| EP-0802194-A2 | Novel thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORPORATION (JP) | 1997-10-22 | — | — | EP | disclosed |