Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14008598 | 0.74 | TYR (0.50) | TYRMAOAMAPTALDH1A1ALOX15 | |
| SCHEMBL14008639 | 0.72 | TYR (0.51) | TYRMAOAMAPTALDH1A1ALOX15 | |
| SCHEMBL6670897 | 0.72 | STK17B (0.47) | TYRMAOAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL6421978 | 0.69 | TYR (0.49) | TYRMAOAMAPTALDH1A1ALOX15 | |
| SCHEMBL7549906 | 0.69 | TYR (0.51) | TYRMAOAMAPTMAOBKMT2A | |
| SCHEMBL7545914 | 0.69 | TYR (0.49) | TYRMAOAMAPTALDH1A1HSD17B10 | |
| SCHEMBL7567696 | 0.67 | STK17B (0.42) | TYRMAOAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL6823698 | 0.66 | TYR (0.43) | TYRMAOAMAPTALDH1A1ALOX15 | |
| SCHEMBL6820551 | 0.66 | TYR (0.46) | TYRMAOAMAPTALDH1A1ALOX15 | |
| SCHEMBL6424333 | 0.66 | TYR (0.46) | TYRMAOAMAPTALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968202-B1 | Process for preparing photoactive coumarin dervatives | CLARIANT FINANCE BVI LTD (VG) | 2002-07-03 | — | — | EP | disclosed |
| EP-0977747-B1 | PHOTOACTIVE COUMARIN DERIVATIVES | CLARIANT FINANCE BVI LTD (VG) | 2002-06-12 | — | — | EP | disclosed |
| EP-0977747-A1 | PHOTOACTIVE COUMARIN DERIVATIVES | CLARIANT INTERNATIONAL LTD. (CH) | 2000-02-09 | — | — | EP | disclosed |
| EP-0968202-A1 | PROCESS FOR PREPARING PHOTOACTIVE COUMARIN DERIVATIVES | CLARIANT INTERNATIONAL LTD. (CH) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998039317-A1 | PROCESS FOR PREPARING PHOTOACTIVE COUMARIN DERIVATIVES | CLARIANT INTERNATIONAL LTD. (CH) | 1998-09-11 | — | — | WO | disclosed |
| WO-1998039319-A1 | PHOTOACTIVE COUMARIN DERIVATIVES | CLARIANT INTERNATIONAL LTD. (CH) | 1998-09-11 | — | — | WO | disclosed |
| US-5726296-A | PHOTORESISTS | HOECHST CELANESE CORP. (US) | 1998-03-10 | — | — | US | disclosed |
| US-5726295-A | Photoactive coumarin derivatives | HOECHST CELANESE CORP. (US) | 1998-03-10 | — | — | US | disclosed |