Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 5/20 | 0.49 |
| ▸ | STK17B | O94768 | 2/20 | 0.47 |
| ▸ | TOP1 | P11387 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549906 | 0.87 | TYR (0.51) | TYRSTK17BRAB9AMAPTMEN1 | |
| SCHEMBL11219422 | 0.81 | TYR (0.54) | TYRSTK17BTOP1RAB9AMAPT | |
| SCHEMBL7578571 | 0.79 | STK17B (0.39) | TYRSTK17BRAB9AMAPTALDH1A1 | |
| SCHEMBL28936587 | 0.79 | TYR (0.53) | TYRSTK17BTOP1RAB9AMAPT | |
| SCHEMBL29391946 | 0.79 | TYR (0.53) | TYRSTK17BTOP1RAB9AMAPT | |
| SCHEMBL6670897 | 0.78 | STK17B (0.47) | TYRSTK17BALDH1A1MEN1KMT2A | |
| SCHEMBL6671599 | 0.77 | MAOA (0.32) | STK17BALDH1A1MAOAMAOBHSD17B10 | |
| SCHEMBL7546181 | 0.74 | TOP1 (0.49) | TOP1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL7567696 | 0.72 | STK17B (0.42) | TYRSTK17BALDH1A1MEN1KMT2A | |
| SCHEMBL7547313 | 0.69 | TYR (0.47) | TYRTOP1MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977747-A1 | PHOTOACTIVE COUMARIN DERIVATIVES | CLARIANT INTERNATIONAL LTD. (CH) | 2000-02-09 | — | — | EP | claimed |
| WO-1998039319-A1 | PHOTOACTIVE COUMARIN DERIVATIVES | CLARIANT INTERNATIONAL LTD. (CH) | 1998-09-11 | — | — | WO | claimed |
| EP-0968202-B1 | Process for preparing photoactive coumarin dervatives | CLARIANT FINANCE BVI LTD (VG) | 2002-07-03 | — | — | EP | disclosed |
| EP-0977747-B1 | PHOTOACTIVE COUMARIN DERIVATIVES | CLARIANT FINANCE BVI LTD (VG) | 2002-06-12 | — | — | EP | disclosed |
| EP-0977747-A1 | PHOTOACTIVE COUMARIN DERIVATIVES | CLARIANT INTERNATIONAL LTD. (CH) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998039319-A1 | PHOTOACTIVE COUMARIN DERIVATIVES | CLARIANT INTERNATIONAL LTD. (CH) | 1998-09-11 | — | — | WO | disclosed |
| US-5726296-A | PHOTORESISTS | HOECHST CELANESE CORP. (US) | 1998-03-10 | — | — | US | disclosed |
| US-5726295-A | Photoactive coumarin derivatives | HOECHST CELANESE CORP. (US) | 1998-03-10 | — | — | US | disclosed |