Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6043694 | 1.00 | NPC1 (0.40) | NPC1SMN1; SMN2HTTGAACES2 | |
| SCHEMBL11094656 | 0.97 | — | — | |
| SCHEMBL17062485 | 0.92 | — | — | |
| SCHEMBL382211 | 0.85 | — | — | |
| SCHEMBL7523411 | 0.76 | CES2 (0.38) | NPC1SMN1; SMN2HTTGAACES2 | |
| SCHEMBL176778 | 0.76 | EPHX1 (0.41) | NPC1SMN1; SMN2CES2CES1GRIK1 | |
| SCHEMBL6043876 | 0.76 | EPHX1 (0.41) | NPC1SMN1; SMN2CES2CES1GRIK1 | |
| SCHEMBL28033618 | 0.76 | CES2 (0.38) | NPC1SMN1; SMN2CES2CES1GRIK1 | |
| SCHEMBL3602770 | 0.74 | — | — | |
| SCHEMBL23749603 | 0.74 | HTT (0.47) | NPC1SMN1; SMN2HTTGAACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 266 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040102629-A1 | Thioquinazolinone derivatives and combinatorial libraries thereof | LION BIOSCIENCE, AG. (DE) | 2004-05-27 | — | — | US | claimed |
| EP-0820444-A1 | 1-PHENYLPYRAZOLE-3-CARBOXAMIDES ACTING ON NEUROTENSIN RECEPTORS | SANOFI (FR) | 1998-01-28 | — | — | EP | claimed |
| WO-1996032382-A1 | 1-PHENYLPYRAZOLE-3-CARBOXAMIDES ACTING ON NEUROTENSIN RECEPTORS | SANOFI (FR) | 1996-10-17 | — | — | WO | claimed |
| JP-9110869-A | — | — | None | — | — | JP | disclosed |
| EP-4245815-A1 | ANTIFOULING COATING MATERIAL COMPOSITION | Nitto Kasei Co., Ltd. (JP) | 2023-09-20 | — | — | EP | disclosed |
| CN-107690434-B | Fused tricyclic imidazopyrazine derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-108699348-B | Coloring composition, ink for inkjet recording, inkjet recording method, and ink cartridge for inkjet printer | 富士胶片株式会社 | 2021-03-12 | — | — | CN | disclosed |
| US-10894898-B2 | Water-based ink for ink-jet recording and ink container | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2021-01-19 | — | — | US | disclosed |
| CN-105829307-B | Tetrahydroimidazopyridine derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2020-07-24 | — | — | CN | disclosed |
| US-10711148-B2 | Coloring composition, ink jet recording ink, ink jet recording method, and ink jet printer cartridge | FUJIFILM CORPORATION (JP) | 2020-07-14 | — | — | US | disclosed |
| EP-3080127-B1 | IMIDAZOPYRIMIDINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB Biopharma SRL (BE) | 2020-06-24 | — | — | EP | disclosed |
| WO-1997005116-A1 | SUBSTITUTED AMINOURACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-13 | — | — | WO | disclosed |
| US-5599386-A | Recording liquid | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-02-04 | — | — | US | disclosed |
| WO-1997001541-A1 | SUBSTITUTED CYANOPHENYL URACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-16 | — | — | WO | disclosed |
| WO-1996032382-A1 | 1-PHENYLPYRAZOLE-3-CARBOXAMIDES ACTING ON NEUROTENSIN RECEPTORS | SANOFI (FR) | 1996-10-17 | — | — | WO | disclosed |
| US-5480478-A | Recording liquid | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0682088-A1 | Monoazo dye having an aminonaphthodisulfonic acid as coupling component and recording liquid containing the same | Mitsubishi Chemical Corporation (JP) | 1995-11-15 | — | — | EP | disclosed |
| EP-0656407-A2 | Recording liquid | Mitsubishi Chemical Corporation (JP) | 1995-06-07 | — | — | EP | disclosed |
| EP-0564960-A1 | Imidazopyridines as angiotensin II antagonists | MERCK PATENT GmbH (DE) | 1993-10-13 | — | — | EP | disclosed |
| EP-0292305-B1 | NOVEL THIAZOLIDIN-4-ONE DERIVATIVES AND ACID ADDITION SALTS THEREOF | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-07-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102629-A1 | Thioquinazolinone derivatives and combinatorial libraries thereof | TTI1, RPS4Y1, TSNAX | NPC1 2936/4885SMN1; SMN2 4688/4885HTT 2280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.