Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994556 | 0.93 | ELANE (0.68) | ELANECTRC | |
| SCHEMBL8536723 | 0.91 | ELANE (0.78) | ELANECTRC | |
| SCHEMBL7398785 | 0.88 | CMA1 (0.67) | ELANECTRC | |
| SCHEMBL8994544 | 0.88 | ELANE (0.77) | ELANECTRC | |
| SCHEMBL8994538 | 0.87 | ELANE (0.73) | ELANECTRC | |
| SCHEMBL7274370 | 0.86 | ELANE (1.00) | ELANECTRC | |
| SCHEMBL7399566 | 0.85 | ELANE (0.62) | ELANECTRC | |
| SCHEMBL7544232 | 0.84 | ELANE (0.81) | ELANECTRC | |
| SCHEMBL7404982 | 0.83 | CMA1 (0.65) | ELANECTRC | |
| SCHEMBL7440632 | 0.81 | ELANE (0.80) | ELANECTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721222-A | Heterocyclic ketones | ZENECA LIMITED (GB) | 1998-02-24 | — | — | US | disclosed |
| US-5486529-A | Certain pyridyl ketones for treating diseases involving leukocyte elastase | ZENECA LIMITED (GB) | 1996-01-23 | — | — | US | disclosed |
| EP-0636142-A1 | LACTAM PEPTIDES HAVING HLE INHIBITING ACTIVITY | ZENECA LIMITED (GB) | 1995-02-01 | — | — | EP | disclosed |
| WO-1993021209-A1 | LACTAM PEPTIDES HAVING HLE INHIBITING ACTIVITY | ZENECA LIMITED (GB) | 1993-10-28 | — | — | WO | disclosed |