Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 17/20 | 0.73 |
| ▸ | CMA1 | P23946 | 3/20 | 0.59 |
| ▸ | CTRC | Q99895 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400416 | 0.87 | ELANE (0.75) | ELANECTRC | |
| SCHEMBL7547485 | 0.87 | ELANE (0.75) | ELANECTRC | |
| SCHEMBL8536723 | 0.86 | ELANE (0.78) | ELANECTRC | |
| SCHEMBL7274370 | 0.85 | ELANE (1.00) | ELANECTRC | |
| SCHEMBL8994556 | 0.83 | ELANE (0.68) | ELANECTRC | |
| SCHEMBL7439651 | 0.81 | ELANE (0.77) | ELANECTRC | |
| SCHEMBL7443054 | 0.77 | ELANE (0.65) | ELANECTRC | |
| SCHEMBL7436681 | 0.76 | ELANE (0.82) | ELANECTRC | |
| SCHEMBL7398785 | 0.75 | CMA1 (0.67) | ELANECMA1CTRC | |
| SCHEMBL8994544 | 0.75 | ELANE (0.77) | ELANECTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486529-A | Certain pyridyl ketones for treating diseases involving leukocyte elastase | ZENECA LIMITED (GB) | 1996-01-23 | — | — | US | disclosed |