Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541521 | 0.92 | SMN1; SMN2 (0.50) | SMN1; SMN2DYRK1AALDH1A1MAPTALOX5 | |
| SCHEMBL7544620 | 0.92 | MAPT (0.50) | SMN1; SMN2ALDH1A1MAPTPTGER4ALOX5 | |
| SCHEMBL7548242 | 0.91 | DYRK1A (0.49) | SMN1; SMN2DYRK1AALDH1A1MAPTPTGER4 | |
| SCHEMBL7544993 | 0.90 | DYRK1A (0.47) | SMN1; SMN2DYRK1AALDH1A1MAPTPTGER4 | |
| SCHEMBL7541330 | 0.90 | DYRK1A (0.47) | SMN1; SMN2DYRK1APTGER4ALOX5EPHX2 | |
| SCHEMBL7542976 | 0.89 | ALOX5 (0.48) | SMN1; SMN2ALDH1A1MAPTPTGER4ALOX5 | |
| SCHEMBL7548069 | 0.88 | ALOX5 (0.62) | SMN1; SMN2DYRK1AALDH1A1MAPTPTGER4 | |
| SCHEMBL7542041 | 0.87 | DYRK1A (0.51) | SMN1; SMN2DYRK1AALDH1A1MAPTPTGER4 | |
| SCHEMBL7541360 | 0.87 | ALOX5 (0.57) | SMN1; SMN2DYRK1APTGER4ALOX5EPHX2 | |
| SCHEMBL7548440 | 0.87 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1MAPTALOX5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795550-B1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0795550-A1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |