SCHEMBL7541360

SCHEMBL7541360

CC(=O)Nc1ccc(OCc2nc3cc(F)ccc3s2)cc1Cl

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 16/20 0.57
EPHX2 P34913 13/20 0.57
ALOX5AP P20292 1/20 0.51
DYRK1A Q13627 1/20 0.51
PTGER4 P35408 2/20 0.49
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7548803 0.92 ALOX5 (0.55) ALOX5EPHX2ALOX5APDYRK1ANPC1
SCHEMBL7551643 0.90 ALOX5 (0.56) ALOX5EPHX2ALOX5APNPC1RAB9A
SCHEMBL7548069 0.89 ALOX5 (0.62) ALOX5EPHX2ALOX5APDYRK1APTGER4
SCHEMBL7550272 0.89 ALOX5 (0.53) ALOX5EPHX2ALOX5APNPC1RAB9A
SCHEMBL7550204 0.89 DYRK1A (0.56) ALOX5EPHX2ALOX5APDYRK1ANPC1
SCHEMBL7541264 0.89 ALOX5 (0.58) ALOX5EPHX2ALOX5APDYRK1ANPC1
SCHEMBL7542041 0.88 DYRK1A (0.51) ALOX5EPHX2ALOX5APDYRK1APTGER4
SCHEMBL7543772 0.87 DYRK1A (0.53) ALOX5EPHX2ALOX5APDYRK1A
SCHEMBL7547564 0.87 SMN1; SMN2 (0.50) ALOX5EPHX2ALOX5APDYRK1APTGER4
SCHEMBL7544335 0.87 ALOX5 (0.71) ALOX5EPHX2ALOX5APNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0795550-B1 Aniline derivatives having herbicidal activity their preparation and their use SANKYO CO (JP) 2002-06-05 EP disclosed
US-5736487-A HERBICIDES SANKYO COMPANY, LIMITED (JP) 1998-04-07 US disclosed
EP-0795550-A1 Aniline derivatives having herbicidal activity their preparation and their use SANKYO COMPANY LIMITED (JP) 1997-09-17 EP disclosed