Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 2/20 | 0.56 |
| ▸ | CCKBR | P32239 | 14/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7547752 | 1.00 | CCKAR (0.56) | CCKARCCKBRCYP3A4MAPTTSHR | |
| SCHEMBL7544378 | 0.93 | CCKAR (0.54) | CCKARCCKBRCYP3A4MAPTTSHR | |
| SCHEMBL7544373 | 0.93 | CCKAR (0.54) | CCKARCCKBRCYP3A4MAPTTSHR | |
| SCHEMBL7546601 | 0.89 | CCKAR (0.57) | CCKARCCKBRCYP3A4MAPTTSHR | |
| SCHEMBL7546598 | 0.89 | CCKAR (0.57) | CCKARCCKBRCYP3A4MAPTTSHR | |
| SCHEMBL7545728 | 0.89 | CCKBR (0.57) | CCKARCCKBRCYP3A4MAPTTSHR | |
| SCHEMBL7545729 | 0.89 | CCKBR (0.57) | CCKARCCKBRCYP3A4MAPTTSHR | |
| SCHEMBL8534456 | 0.85 | CCKBR (0.66) | CCKARCCKBRCYP3A4MAPTTSHR | |
| SCHEMBL9055145 | 0.85 | CCKBR (0.66) | CCKARCCKBRCYP3A4MAPTTSHR | |
| SCHEMBL9054859 | 0.84 | CCKBR (0.68) | CCKARCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020183313-A1 | 1,4-benzodiazepinones and their uses as CCK antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-05 | — | — | US | disclosed |
| US-20020002163-A1 | 1,4-benzodiazepinones and their uses as CCK antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | US | disclosed |
| US-6291452-B1 | CHOLECYSTOKININ ANTAGONISTS. | FUJISAWA PHARMACETICAL CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020002163-A1 | 1,4-benzodiazepinones and their uses as CCK antagonists | CCKAR, CCKBR, GABRA4 | CCKAR 1/4885CCKBR 2/4885CYP3A4 318/4885 |
| US-20020183313-A1 | 1,4-benzodiazepinones and their uses as CCK antagonists | CCKAR, CCKBR, GABRA4 | CCKAR 1/4885CCKBR 2/4885CYP3A4 318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.