Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.69 |
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.57 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.57 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.57 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30480036 | 0.99 | HDAC1 (0.70) | HDAC1HDAC6CA1CA2CSNK2A2 | |
| SCHEMBL6925178 | 0.99 | HDAC1 (0.70) | HDAC1HDAC6CA1CA2CSNK2A2 | |
| SCHEMBL7547761 | 0.96 | HDAC1 (0.67) | HDAC1HDAC6CA1CA2CSNK2A2 | |
| SCHEMBL25233958 | 0.87 | HDAC6 (0.64) | HDAC1HDAC6CA1CA2CSNK2A2 | |
| SCHEMBL6925477 | 0.84 | PTGS1 (0.65) | HDAC1HDAC6CA1CA2CSNK2A2 | |
| SCHEMBL6921299 | 0.84 | HDAC1 (0.69) | HDAC1HDAC6CA1CA2CSNK2A2 | |
| SCHEMBL6925062 | 0.83 | PTGS1 (0.58) | HDAC1HDAC6CA1CA2CSNK2A2 | |
| SCHEMBL14894467 | 0.82 | HDAC6 (1.00) | HDAC1HDAC6 | |
| SCHEMBL6755499 | 0.81 | HDAC1 (0.56) | HDAC1HDAC6CA1CA2ALB | |
| SCHEMBL14895937 | 0.81 | HDAC6 (0.75) | HDAC1HDAC6CA1CA2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210329-A2 | AMINOALKOXY CARBAZOLES AND THEIR USE AS 5-HT LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001017963-A2 | AMINOALKOXY CARBAZOLES AND THEIR USE AS 5-HT LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2001-03-15 | — | — | WO | disclosed |