Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 4/20 | 0.42 |
| ▸ | CYP26B1 | Q9NR63 | 4/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548008 | 0.84 | CYP26A1 (0.59) | CYP26A1CYP26B1ALDH1A1HSD17B10RAB9A | |
| SCHEMBL5737184 | 0.81 | CYP26A1 (0.38) | CYP26A1CYP26B1MEN1KMT2AGSTP1 | |
| SCHEMBL14194533 | 0.70 | CYP26A1 (0.40) | CYP26A1CYP26B1LMNAMAPTKDM4E | |
| SCHEMBL718523 | 0.70 | MAPT (0.56) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL9081470 | 0.70 | LMNA (0.61) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL5736806 | 0.69 | CYP26A1 (0.40) | CYP26A1CYP26B1 | |
| SCHEMBL5735116 | 0.68 | CYP26A1 (0.44) | CYP26A1CYP26B1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL5736408 | 0.68 | CYP26A1 (0.45) | CYP26A1CYP26B1MEN1KMT2ALMNA | |
| SCHEMBL5737183 | 0.68 | CYP26A1 (0.56) | CYP26A1CYP26B1RAB9ACYP3A4 | |
| SCHEMBL5738447 | 0.68 | RARB (0.42) | CYP26A1MEN1KMT2AGSTP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193578-A1 | Compounds having activity as inhibitors of cytochrome P450RAI | ALLERGAN, INC. | 2002-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193578-A1 | Compounds having activity as inhibitors of cytochrome P450RAI | RARA, RARB, RARG | CYP26A1 4/4885CYP26B1 5/4885NR3C2 215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.