SCHEMBL7548121

SCHEMBL7548121

CCOC(=O)C(Oc1ccc([N+](=O)[O-])cc1)C(=O)OC(C)(C)C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.51
CRHBP P24387 1/20 0.51
CRHR2 Q13324 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.50
HTR2A P28223 1/20 0.44
BCL9 O00512 1/20 0.44
CTNNB1 P35222 1/20 0.44
KMT2A Q03164 4/20 0.44
LMNA P02545 4/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
MAPK1 P28482 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MEN1 O00255 2/20 0.43
ITGA4 P13612 1/20 0.42
ITGB7 P26010 1/20 0.42
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 4/20 0.41
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15516165 0.91 MAPT (0.59) MAPTCRHBPCRHR2L3MBTL1HTR2A
SCHEMBL8949976 0.83 MAPT (0.54) MAPTCRHBPCRHR2L3MBTL1HTR2A
SCHEMBL8770261 0.79 HTR2A (0.45) MAPTCRHBPCRHR2L3MBTL1HTR2A
SCHEMBL655938 0.78 MAPT (0.58) MAPTCRHBPCRHR2L3MBTL1HTR2A
SCHEMBL3535210 0.77 MAPT (0.56) MAPTCRHBPCRHR2L3MBTL1HTR2A
SCHEMBL30098369 0.77 MAPT (0.56) MAPTCRHBPCRHR2L3MBTL1HTR2A
SCHEMBL11708706 0.77 MAPT (0.56) MAPTCRHBPCRHR2L3MBTL1HTR2A
SCHEMBL7749276 0.77 MAPT (0.53) MAPTCRHBPCRHR2L3MBTL1HTR2A
SCHEMBL9306479 0.77 KMT2A (0.54) MAPTCRHBPCRHR2L3MBTL1KMT2A
SCHEMBL6391326 0.75 MAPT (0.57) MAPTCRHBPCRHR2L3MBTL1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0720047-B1 Photographic element containing a stable aryloxypyrazolone coupler and process employing the same EASTMAN KODAK CO (US) 2002-07-03 EP disclosed
US-6365334-B1 STABILITY, IMAGES EASTMAN KODAK COMPANY 2002-04-02 US disclosed
EP-0658806-B1 Photographic elements containing aryloxypyrazolone couplers and sulfur containing stabilizers EASTMAN KODAK CO (US) 2001-02-07 EP disclosed
US-5576167-A Photographic element containing a stable aryloxypyrazolone coupler and process employing same EASTMAN KODAK COMPANY (US) 1996-11-19 US disclosed
EP-0720047-A2 Photographic element containing a stable aryloxypyrazolone coupler and process employing the same EASTMAN KODAK COMPANY (US) 1996-07-03 EP disclosed
EP-0658806-A1 Photographic elements containing aryloxypyrazolone couplers and sulfur containing stabilizers EASTMAN KODAK COMPANY (US) 1995-06-21 EP disclosed