Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | BCL9 | O00512 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986077 | 0.82 | HTR2A (0.46) | HTR2AMAPTMEN1KMT2AHTT | |
| SCHEMBL6609952 | 0.79 | ALDH1A1 (0.49) | MAPTMEN1KMT2ANPC1LMNA | |
| SCHEMBL7548121 | 0.79 | MAPT (0.51) | HTR2AMAPTMEN1KMT2AHTT | |
| SCHEMBL24058871 | 0.77 | MGLL (0.52) | HTR2AMAPTMEN1KMT2AHTT | |
| SCHEMBL19871006 | 0.77 | MGLL (0.52) | HTR2AMAPTMEN1KMT2AHTT | |
| SCHEMBL3527114 | 0.76 | ALDH1A1 (0.51) | MAPTMEN1KMT2ANPC1LMNA | |
| SCHEMBL29101053 | 0.75 | ALDH1A1 (0.51) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL22013867 | 0.75 | ALDH1A1 (0.51) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL550633 | 0.75 | KMT2A (0.52) | MAPTMEN1KMT2ARAB9ALMNA | |
| SCHEMBL4828326 | 0.74 | MEN1 (0.48) | MAPTMEN1KMT2AHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632019-B1 | Acylureas | ZENECA LTD (GB) | 1997-09-24 | — | — | EP | disclosed |
| US-5576334-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1996-11-19 | — | — | US | disclosed |
| EP-0632019-A1 | Acylureas | ZENECA LIMITED (GB) | 1995-01-04 | — | — | EP | disclosed |