Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.72 |
| ▸ | RAB9A | P51151 | 5/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.68 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | STAT1 | P42224 | 1/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.64 |
| ▸ | RELA | Q04206 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548125 | 0.95 | NPC1 (0.73) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7551599 | 0.90 | NPC1 (0.76) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7544973 | 0.87 | NPC1 (0.77) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7551577 | 0.85 | ALOX5 (0.69) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7542600 | 0.84 | NPC1 (1.00) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7544458 | 0.83 | NPC1 (0.79) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7547219 | 0.83 | EPHX2 (0.68) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7545168 | 0.83 | NPC1 (0.71) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8769691 | 0.82 | EPHX2 (0.84) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7541569 | 0.81 | NPC1 (0.76) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795550-B1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0795550-A1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |