Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 19/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548174 | 0.88 | PLAT (0.40) | CCR5PRCP | |
| SCHEMBL5763292 | 0.83 | PLAT (0.42) | CCR5PRCP | |
| Hydrochloric Acid SCHEMBL7660201 | 0.82 | PLAT (0.42) | CCR5PRCP | |
| SCHEMBL5763782 | 0.79 | PLAT (0.44) | CCR5PRCP | |
| SCHEMBL5461506 | 0.73 | CCR5 (0.46) | CCR5PRCPKCNH2 | |
| Hydrochloric Acid SCHEMBL5764395 | 0.72 | CCR5 (0.45) | CCR5PRCPKCNH2 | |
| SCHEMBL5764492 | 0.71 | CCR5 (0.47) | CCR5PRCP | |
| SCHEMBL5764913 | 0.70 | PLAT (0.38) | CCR5KCNH2 | |
| Hydrochloric Acid SCHEMBL5762051 | 0.70 | CCR5 (0.47) | CCR5 | |
| SCHEMBL27643633 | 0.70 | CCR5 (0.49) | CCR5PRCPKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192133-A1 | N-CYCLOPENTYL MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Merck & Co., Inc. (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000076972-A1 | N-CYCLOPENTYL MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2000-12-21 | — | — | WO | disclosed |