Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 5/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | CCR5 | P51681 | 4/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5763292 | 0.96 | PLAT (0.42) | PLATPRCPHTR2CSLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL7660201 | 0.94 | PLAT (0.42) | PLATPRCPHTR2CSLC6A2SLC6A4 | |
| SCHEMBL5763782 | 0.92 | PLAT (0.44) | PLATPRCPHTR2CSLC6A2SLC6A4 | |
| SCHEMBL7548170 | 0.88 | CCR5 (0.41) | PRCPCCR5 | |
| SCHEMBL5461506 | 0.86 | CCR5 (0.46) | PLATPRCPHTR2CSLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL5764395 | 0.85 | CCR5 (0.45) | PLATPRCPHTR2CSLC6A2SLC6A4 | |
| SCHEMBL5764492 | 0.84 | CCR5 (0.47) | PLATPRCPHTR2CCCR5 | |
| SCHEMBL5764913 | 0.84 | PLAT (0.38) | PLATCCR5 | |
| Hydrochloric Acid SCHEMBL5762051 | 0.83 | CCR5 (0.47) | PLATHTR2CCCR5 | |
| SCHEMBL5761444 | 0.81 | HTR6 (0.42) | PLATCCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192133-A1 | N-CYCLOPENTYL MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Merck & Co., Inc. (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000076972-A1 | N-CYCLOPENTYL MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2000-12-21 | — | — | WO | disclosed |