Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 14/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7542502 | 0.91 | MAPT (0.46) | CETPMAPTRXFP1THRBSMN1; SMN2 | |
| SCHEMBL7543749 | 0.87 | ALOX5 (0.45) | CETPMAPTSMN1; SMN2POLBALOX5 | |
| SCHEMBL7542942 | 0.85 | AGPAT2 (0.43) | CETPMAPTRXFP1THRBSMN1; SMN2 | |
| SCHEMBL7544432 | 0.85 | ALOX5 (0.44) | CETPMAPTTHRBSMN1; SMN2POLB | |
| SCHEMBL7544004 | 0.83 | MAPT (0.46) | CETPMAPTTHRBSMN1; SMN2TP53 | |
| SCHEMBL7549421 | 0.82 | MAPK13 (0.41) | MAPTPOLBALOX5EPHX2 | |
| SCHEMBL7542652 | 0.82 | ALOX5 (0.43) | SMN1; SMN2ALOX5EPHX2 | |
| SCHEMBL7542425 | 0.82 | ALOX5 (0.48) | MAPTTP53POLBALOX5EPHX2 | |
| SCHEMBL7543899 | 0.81 | MAPT (0.45) | CETPMAPTPOLBALOX5EPHX2 | |
| SCHEMBL7548836 | 0.80 | MAPT (0.46) | MAPTRXFP1THRBSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795550-B1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0795550-A1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |