Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7547607 | 0.92 | MAPT (0.46) | MAPTLMNARXFP1CEPT1THRB | |
| SCHEMBL7542942 | 0.91 | AGPAT2 (0.43) | MAPTLMNARXFP1TSHRCEPT1 | |
| SCHEMBL7541702 | 0.89 | MAPT (0.45) | MAPTLMNARXFP1TSHRTHRB | |
| SCHEMBL7547636 | 0.89 | DRD2 (0.46) | MAPTLMNARXFP1CEPT1THRB | |
| SCHEMBL7541140 | 0.89 | LMNA (0.53) | MAPTLMNARXFP1THRBRAB9A | |
| SCHEMBL7542425 | 0.87 | ALOX5 (0.48) | MAPTLMNARAB9ANPC1MEN1 | |
| SCHEMBL7541056 | 0.86 | CETP (0.44) | TSHRPPARDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7541102 | 0.85 | NPC1 (0.45) | MAPTLMNAHTTCEPT1RAB9A | |
| SCHEMBL7541510 | 0.84 | AGPAT2 (0.50) | MAPTLMNARXFP1TSHRRAB9A | |
| SCHEMBL7544004 | 0.84 | MAPT (0.46) | MAPTLMNATSHRTHRBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795550-B1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0795550-A1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |