Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 5/20 | 0.33 |
| ▸ | MAOA | P21397 | 5/20 | 0.33 |
| ▸ | MAOB | P27338 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548455 | 0.85 | TSHR (0.38) | TSHRSLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL10078283 | 0.75 | TSHR (0.41) | TSHRSLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL573946 | 0.75 | TSHR (0.41) | TSHRSLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL7550415 | 0.72 | TSHR (0.35) | TSHRKDM1AMAOAMAOBLMNA | |
| SCHEMBL7549783 | 0.70 | KDM1A (0.38) | TSHRKDM1AMAOAMAOB | |
| SCHEMBL21954832 | 0.68 | TSHR (0.41) | TSHRKDM1AMAOAMAOBMEN1 | |
| SCHEMBL7550942 | 0.67 | SLC6A2 (0.45) | TSHRSLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL7550459 | 0.66 | ALDH1A1 (0.34) | TSHR | |
| SCHEMBL10798707 | 0.66 | TSHR (0.42) | TSHRSLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL16377614 | 0.65 | TSHR (0.50) | TSHRKDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002051883-A1 | SYNTHESIS OF NOVEL HETEROCYCLIC MOLECULES OXYGENATED BY METATHESIS REACTION ON SOLID SUPPORT USING NOVEL SILYLATED LINKERS | AVENTIS PHARMA S.A. (FR) | 2002-07-04 | — | — | WO | disclosed |