Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | KDM1A | O60341 | 7/20 | 0.32 |
| ▸ | MAOA | P21397 | 7/20 | 0.32 |
| ▸ | MAOB | P27338 | 7/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548455 | 0.83 | TSHR (0.38) | TSHRKDM1AMAOAMAOBLMNA | |
| SCHEMBL7549783 | 0.77 | KDM1A (0.38) | TSHRKDM1AMAOAMAOB | |
| SCHEMBL7550459 | 0.72 | ALDH1A1 (0.34) | TSHR | |
| SCHEMBL14838587 | 0.70 | CHRM2 (0.39) | TSHRLMNACYP3A4 | |
| SCHEMBL15927760 | 0.70 | ALDH1A1 (0.34) | TSHRLMNACYP3A4 | |
| SCHEMBL21954832 | 0.66 | TSHR (0.41) | TSHRKDM1AMAOAMAOB | |
| SCHEMBL3973022 | 0.65 | CHRM2 (0.40) | KDM1AMAOAMAOBCYP3A4 | |
| SCHEMBL7107611 | 0.65 | CHRM2 (0.40) | KDM1AMAOAMAOBCYP3A4 | |
| SCHEMBL16377614 | 0.63 | TSHR (0.50) | TSHRKDM1AMAOAMAOB | |
| SCHEMBL7787343 | 0.63 | TSHR (0.50) | TSHRKDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002051883-A1 | SYNTHESIS OF NOVEL HETEROCYCLIC MOLECULES OXYGENATED BY METATHESIS REACTION ON SOLID SUPPORT USING NOVEL SILYLATED LINKERS | AVENTIS PHARMA S.A. (FR) | 2002-07-04 | — | — | WO | claimed |
| WO-2002051883-A1 | SYNTHESIS OF NOVEL HETEROCYCLIC MOLECULES OXYGENATED BY METATHESIS REACTION ON SOLID SUPPORT USING NOVEL SILYLATED LINKERS | AVENTIS PHARMA S.A. (FR) | 2002-07-04 | — | — | WO | disclosed |