SCHEMBL754849

SCHEMBL754849

O=S(=O)(C(Br)(Br)Cc1cccc(Br)c1)C(Br)(Br)Cc1cccc(Br)c1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.46
IDO1 P14902 2/20 0.44
AGXT P21549 2/20 0.44
EGFR P00533 5/20 0.42
ERBB2 P04626 5/20 0.42
MAOB P27338 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA5A P35218 1/20 0.40
CA9 Q16790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL751699 0.81 TAAR1 (0.43) TAAR1IDO1AGXTEGFRERBB2
SCHEMBL753767 0.79 ACHE (0.44) TAAR1IDO1MAOB
SCHEMBL754038 0.79 PNMT (0.47) TAAR1IDO1AGXT
SCHEMBL3142824 0.77 TAAR1 (0.54) TAAR1IDO1AGXTMAOBSMN1; SMN2
SCHEMBL751764 0.75 PLCG1 (0.41) TAAR1IDO1EGFRERBB2CA1
SCHEMBL15476972 0.74 TAAR1 (0.50) TAAR1IDO1AGXTMAOBSMN1; SMN2
SCHEMBL3843548 0.74 TAAR1 (0.50) TAAR1IDO1AGXTMAOBSMN1; SMN2
SCHEMBL28442171 0.74 TAAR1 (0.50) TAAR1IDO1AGXTMAOBSMN1; SMN2
SCHEMBL1368311 0.74 TAAR1 (0.50) TAAR1IDO1AGXTEGFRERBB2
SCHEMBL30019965 0.74 TAAR1 (0.50) TAAR1IDO1AGXTEGFRERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2213166-B1 Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone THOR GMBH (DE) 2012-03-21 EP claimed