Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.68 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2767610 | 0.97 | ESR1 (0.72) | ESR1ESR2CA2ALDH1A1ADRA2A | |
| SCHEMBL15082413 | 0.90 | ESR1 (0.62) | ESR1ESR2CA2ALDH1A1ADRA2A | |
| SCHEMBL7553772 | 0.87 | ESR1 (0.59) | ESR1ESR2CA2ALDH1A1ADRA2A | |
| SCHEMBL5611647 | 0.84 | ESR1 (0.62) | ESR1ESR2CA2ALDH1A1ADRA2A | |
| SCHEMBL11554910 | 0.82 | ESR1 (0.59) | ESR1ESR2CA2ALDH1A1ADRA2A | |
| SCHEMBL69344 | 0.82 | ESR1 (1.00) | ESR1ESR2CA2ALDH1A1ADRA2A | |
| SCHEMBL3873458 | 0.82 | ESR1 (1.00) | ESR1ESR2CA2ALDH1A1ADRA2A | |
| SCHEMBL10685072 | 0.82 | ALDH1A1 (0.69) | ESR1ESR2CA2ALDH1A1ADRA2A | |
| SCHEMBL11398334 | 0.80 | ESR1 (0.63) | ESR1ESR2CA2ALDH1A1ADRA2A | |
| SCHEMBL7546992 | 0.78 | ALDH1A1 (0.50) | ESR1ESR2CA2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482990-B1 | Prostaglandin E analogues | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2002-11-19 | — | — | US | disclosed |
| EP-1211241-A1 | PROSTAGLANDIN E ANALOGUES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2002-06-05 | — | — | EP | disclosed |