Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30251819 | 0.85 | TSHR (0.41) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL752442 | 0.81 | TSHR (0.47) | TSHRNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6557218 | 0.81 | TSHR (0.47) | TSHRNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL754896 | 0.80 | TSHR (0.55) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6558474 | 0.80 | TSHR (0.46) | TSHRNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6557397 | 0.80 | TSHR (0.46) | TSHRNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6557419 | 0.79 | TSHR (0.45) | TSHRNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL17447296 | 0.78 | NPC1 (0.68) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4624413 | 0.77 | TSHR (0.55) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1759206 | 0.77 | TSHR (0.55) | TSHRSMN1; SMN2ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9743667-B2 | Substituted benzene fungicides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-08-29 | — | — | US | disclosed |
| US-9198433-B2 | Substituted benzene fungicides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-12-01 | — | — | US | disclosed |
| US-20150335023-A1 | SUBSTITUTED BENZENE FUNGICIDES | FMC CORPORATION | 2015-11-26 | — | — | US | disclosed |
| US-20140323436-A1 | SUBSTITUTED BENZENE FUNGICIDES | FMC CORPORATION | 2014-10-30 | — | — | US | disclosed |
| US-8822521-B2 | Substituted benzene fungicides | E I DU PONT DE NEMOURS AND COMPANY (DE) | 2014-09-02 | — | — | US | disclosed |
| EP-2532240-A2 | Substituted benzene fungicides | E. I. du Pont de Nemours and Company (US) | 2012-12-12 | — | — | EP | disclosed |
| EP-2529624-A2 | Substituted benzene fungicides | E. I. du Pont de Nemours and Company (US) | 2012-12-05 | — | — | EP | disclosed |
| EP-2430921-A2 | Substituted benzene fungicides | E.I. Du Pont De Nemours And Company (US) | 2012-03-21 | — | — | EP | disclosed |
| US-20100120714-A1 | SUBSTITUTED BENZENE FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-05-13 | — | — | US | disclosed |
| CN-101686688-A | substituted benzene fungicides | DU PONT | 2010-03-31 | — | — | CN | disclosed |
| EP-2129225-A2 | SUBSTITUTED BENZENE FUNGICIDES | E. I. Du Pont de Nemours and Company (US) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008124092-A2 | SUBSTITUTED BENZENE FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150335023-A1 | SUBSTITUTED BENZENE FUNGICIDES | NR0B1, CBR3, NR0B2 | TSHR 1053/4885NPC1 3141/4885RAB9A 89/4885 |
| US-20140323436-A1 | SUBSTITUTED BENZENE FUNGICIDES | NR0B1, CBR3, NR0B2 | TSHR 1053/4885NPC1 3141/4885RAB9A 89/4885 |
| US-20100120714-A1 | SUBSTITUTED BENZENE FUNGICIDES | NR0B1, CBR3, NR0B2 | TSHR 1039/4885NPC1 2949/4885RAB9A 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.