Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 5/20 | 0.44 |
| ▸ | RAD52 | P43351 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7543616 | 0.94 | TLR8 (0.44) | TSHRKDM4EPOLBRAD52ALDH1A1 | |
| SCHEMBL7546417 | 0.89 | ALDH1A1 (0.51) | TSHRKDM4EPOLBALDH1A1GAA | |
| SCHEMBL7544070 | 0.87 | TLR8 (0.54) | TSHRKDM4EPOLBALDH1A1GAA | |
| SCHEMBL7550406 | 0.86 | TLR8 (0.55) | TSHRKDM4EALDH1A1GAAHPGD | |
| SCHEMBL7548623 | 0.86 | TLR8 (0.55) | TSHRKDM4EALDH1A1GAAHPGD | |
| SCHEMBL7546965 | 0.86 | TLR8 (0.55) | TSHRKDM4EALDH1A1GAAHPGD | |
| SCHEMBL7550363 | 0.86 | TLR8 (0.55) | TSHRKDM4EALDH1A1GAAHPGD | |
| SCHEMBL7544738 | 0.86 | TLR8 (0.55) | TSHRKDM4EALDH1A1GAAHPGD | |
| SCHEMBL7548612 | 0.83 | NCF1 (0.42) | TSHRKDM4EPOLBALDH1A1GAA | |
| SCHEMBL7542516 | 0.82 | NCF1 (0.41) | TSHRKDM4EPOLBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002046163-A2 | QUINOLINE DERIVATIVES AND THEIR USE AS ANTI-EPILEPTICS | WACKERNAGEL MICHAEL (DE) | 2002-06-13 | — | — | WO | disclosed |