Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6251424 | 0.82 | MEN1 (0.40) | ALDH1A1KDM4EF2PLGPRSS1 | |
| SCHEMBL6251422 | 0.82 | MEN1 (0.40) | ALDH1A1KDM4EF2PLGPRSS1 | |
| SCHEMBL8867994 | 0.81 | PBRM1 (0.46) | ALDH1A1KDM4EF2PLGPRSS1 | |
| SCHEMBL8867767 | 0.81 | PBRM1 (0.46) | ALDH1A1KDM4EF2PLGPRSS1 | |
| SCHEMBL16386232 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4ERAB9AMEN1GAA | |
| SCHEMBL17073434 | 0.80 | PBRM1 (0.46) | ALDH1A1KDM4EF2PLGPRSS1 | |
| SCHEMBL18604874 | 0.80 | PBRM1 (0.46) | ALDH1A1KDM4EF2PLGPRSS1 | |
| SCHEMBL10907609 | 0.77 | CYP1A2 (0.42) | ALDH1A1LMNACYP3A4TSHR | |
| SCHEMBL9757698 | 0.77 | CYP1A2 (0.42) | ALDH1A1LMNACYP3A4TSHR | |
| SCHEMBL1193728 | 0.77 | CYP1A2 (0.42) | ALDH1A1LMNACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214288-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE | Targacept Inc. (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001017943-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE | TARGACEPT, INC. (US) | 2001-03-15 | — | — | WO | disclosed |